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Cdc25C downregulation delays cell cycle progression through G2/M. (a–c) U2OS cells were transfected with control or Cdc25C siRNA. Progression through the cell cycle of synchronized cells collected at 14–22 h after release from thymidine block was analyzed by flow cytometry. Representative cell cycle profiles (a), protein levels in the cells extracts (b) and the average of three independent experiments (c) are shown.
