Association of metabolically healthy obesity with cardiovascular disease and all-cause mortality (Odds ratios and 95% confidence intervals) in 5841 MESA participants. MHN=Metabolically heathy normal weight; MHO=Metabolically healthy obesity; MUO=Metabolically unhealthy obesity (categories are mutually exclusive). Metabolically healthy indicates <3 metabolic syndrome components. Unhealthy indicates 3 or more metabolic syndrome components. All models adjusted for age, sex, race/ethnicity, education, income, smoking status, LDL cholesterol, and statin use. Sample sizes: At baseline n=3587 for MHN; n=1051 for MHO; n = 1,203 for MUO. For transition across follow-up n = 2,751 for MHN; n = 550 for MHO throughout; n = 501 for MHO to MUO; and n = 1,203 for MUO.