Table 5.
Associations between lifetime Bipolar I and II disorders in probands and Hypomania Symptom Checklist-32 subscale scores in relatives (N=154)
| Hypomania Symptom Checklist-32 in relatives | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| HCL total score | HCL Activity/Increased energy score | HCL Distractibility/ Irritability score | HCL Novelty seeking/ Disinhibition score | HCL Substance use score | ||||||
|
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| Estimate1 | p-value | Estimate1 | p-value | Estimate1 | p-value | Estimate1 | p-value | Estimate1 | p-value | |
| Intercept | 21.72 | <.0001 | 9.27 | <.0001 | 2.78 | <.0001 | 5.06 | <.0001 | 0.25 | 0.127 |
| PROBAND | ||||||||||
| Bipolar I | 2.18 | 0.101 | 0.26 | 0.669 | 0.65 | 0.078 | 0.55 | 0.135 | 0.14 | 0.158 |
| Bipolar II | −0.66 | 0.604 | −0.31 | 0.594 | −0.32 | 0.374 | 0.07 | 0.844 | −0.04 | 0.677 |
| RELATIVE | ||||||||||
| Age | −0.09 | 0.002 | −0.03 | 0.007 | −0.01 | 0.238 | −0.03 | 0.001 | 0.00 | 0.865 |
| Sex | −2.10 | 0.039 | −0.03 | 0.937 | −0.39 | 0.180 | −0.93 | 0.002 | −0.11 | 0.122 |
| Bipolar I | 3.76 | 0.046 | 0.51 | 0.534 | 2.48 | <.0001 | 0.47 | 0.365 | 0.04 | 0.754 |
| Bipolar II | 3.81 | 0.016 | 0.68 | 0.322 | 1.52 | 0.001 | 0.27 | 0.538 | 0.41 | 0.0004 |
Abbreviation: HCL, Hypomania Symptom Checklist-32.
Linear mixed model.
Statistically significant results are in bold.
P-values are in italic.