Figure 1.

Number of publications (bar graphs) and cumulative number of citations from the previous years (dots) related to the topics of protein design and computational protein design. The term ‘computational protein design’ here also including similar terms such as ‘automated,’ ‘computer-aided,’ ‘ab initio’ and ‘first principle’ protein design while the term ‘de novo’ protein design is excluded, as it is not necessarily referring to ‘automated protein design.’ Data is taken from web of science.