Table 2.

Estimated Relative Risk for Incident Hypertension at Year 25 or Year 30 Follow-up Visits by C-terminal Fibroblast Growth Factor-23 (cFGF23) Quartile

cFGF23 (RU/ml) quartile	Incident Hypertension n (%)	Unadjusted RR (95% CI)	Model 1* RR (95% CI)	Model 2† RR (95% CI)
29.8–62.0	119/439 (27.1%)	Ref	Ref	Ref
62.1–77.0	151/437 (34.6%)	1.27 (1.04, 1.56)	1.32 (1.08, 1.61)	1.31 (1.07, 1.60)
77.1–103.2	173/443 (39.1%)	1.44 (1.19, 1.75)	1.41 (1.16, 1.72)	1.41 (1.16, 1.72)
≥103.3	175/439 (39.9%)	1.47 (1.21, 1.78)	1.48 (1.22, 1.79)	1.45 (1.18, 1.77)
P for Trend		<0.0001	<0.0001	0.0002

^*Model 1 is adjusted for age, sex, race, education, and study center.

^†Model 2 adjusted for the Model 1 variables plus body mass index, smoking status, physical activity, Triglyceride/high density lipoprotein ratio, estimated glomerular filtration rate and urine albumin to creatinine ratio.

RR, Relative Risk; CI, Confidence Interval