Table 1.
Characteristics of the CGM-assessed hypoglycaemia cohort
| Characteristic | C-peptide < 200 pmol/l | C-peptide > 600 pmol/l | p value |
|---|---|---|---|
| No. of participants | 17 | 17 | – |
| C-peptide, pmol/l | 38.9 (10.3, 67.4) | 1238.3 (906.5, 1570.1) | – |
| Mean glucose on CGM, mmol/l | 10.2 (9.1, 11.3) | 9.9 (8.6, 11.1) | 0.50 |
| HbA1c, mmol/mol | 72.0 (65.5, 78.5) | 72.2 (66.1, 78.3) | 0.88 |
| HbA1c, % | 8.7 (8.1, 9.3) | 8.7 (8.4, 9.3) | 0.88 |
| Male sex, n (%) | 11 (65) | 11 (65) | – |
| Age, years | 72.8 (68.4, 77.2) | 71.8 (68.5, 75.1) | 0.71 |
| Diabetes duration, years | 24.5 (19.0, 30.0) | 19.8 (16.8, 22.9) | 0.13 |
| BMI, kg/m2 | 26.6 (24.8, 28.4) | 27.9 (26.1, 29.8) | 0.19 |
| Time to insulin, months | 62 (37, 87) | 111 (76, 145) | 0.03 |
| Total dose of insulin in 24 h, U/kg | 0.71 (0.61, 0.8) | 0.52 (0.39, 0.64) | 0.007 |
| Use of prandial (basal bolus or mixed) insulin, % | 100 | 59 | 0.003 |
| Proportion with ≥ one islet autoantibody, % | 59 (28, 100) | 6 (2, 33) | <0.001 |
Values reported are mean (95% CI) unless stated otherwise