Fig. 2.

Multi-level correlation network calculated in never-smokers, smokers and COPD patients separately. For further explanations, see text. Abbreviations: Abs: absolute count; HSC: Hematopoietic stem cells, HSC prolif: Hematopoietic stem cells with a proliferative marker; TNF: Tumour necrosis factor; TNF R80: Tumour necrosis factor receptor p80; IL: Interleukin; RBC: Red blood cells; WBC: White blood cells; Lympho: Lymphocytes; Segmented: segmented neutrophils; E. Polychrom: Polychromatic erythroblast; E. Basophils: Basophils erythroblast; E. Ortochrom: Ortochromatic erythroblast; B cells: B lymphocytes, Eos: Eosinophils; Mono/Macro: Monocyte/Macrophages; MFI: Mean fluorescence intensity; Neutro: Neutrophil; Bas: Basophil; FEV1: forced expiratory volume in 1st second, DLCO: Diffusing capacity of the lung for carbon monoxide, BMI: body mass index