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. 2018 Jun 15;15:185. doi: 10.1186/s12974-018-1219-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Deletion of Il4ra or Ifngr1 does not alter the quality of reinnervation. A representative image of a retrograde labeled spinal cord in shown (a) with red dots denoting counted cells. The total number of retrograde labeled motor neurons per mouse 8 weeks after sciatic nerve transection and repair are shown (b, c). Il4ra^−/− and control BALB/cJ mice underwent sciatic transection and empty conduit repair with a 3 mm gap (b). Ifngr1^{fl/fl cre/−} and control mice underwent sciatic transection and direct coaptation (c). The cranial tibial muscle weights of the injured limb normalized to the contralateral limb 8 weeks after sciatic nerve transection and repair are shown (d, e). No differences were detected between strains or sexes. n = 6/sex/strain, except male Ifngr1^{fl/fl cre/−} and control (n = 18 each). ANOVA (p > 0.05)