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. 2018 Jun 12;12:1609–1619. doi: 10.2147/DDDT.S164324

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© 2018 Fu et al. This work is published and licensed by Dove Medical Press Limited

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Phorbol 12-myristate 13-acetate (PMA) treatment attenuated the positive effect of Theaflavin (TF) on intracerebral hemorrhage (ICH)-induced neural deficits and brain injury. The rats were randomly divided into ICH + TF group and ICH + TF + PMA group. Corner test (A) and paw placement test (B) were performed to evaluate the effect of PMA on behavioral performance of the ICH rats. The brain water content (C) and evans blue extravasation (D) were measured to assess the brain injury after treating the ICH rats with PMA. Values were expressed as mean ± SD (n =5).

Note: *p<0.05 vs the levels of the ICH + TF group.