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. 2018 Jul 10;29(2):111–127. doi: 10.1089/ars.2017.7097

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Copyright 2018, Mary Ann Liebert, Inc.

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FIG. 3. — Lack of Hmox1 in MSC does not affect their immunomodulatory properties or secretory profile. Number of circulating CD3⁺ T cells (A), CD3⁺AnnexinV⁺ apoptotic T cells (B), or activated CD3⁺CD4⁺CD25^high T cells (C) in control mice or injected i.v. with MSC Hmox1^+/+ or Hmox1^−/− (N = 3–4). Concentration of G-CSF (D), IL-6 (E), LIF (F), LIX (G), CXCL1 (H), MCP-1 (I), RANTES (J), and VEGF (K) in conditioned media from Hmox1^+/+ or Hmox1^−/−MSC assessed with multiplex assay on Luminex platform. Data are shown as mean ± SD, Mann–Whitney, N = 4.