Fig. 5.

Decoding algorithm and illustrative example. (A) Schematic diagram of the decoder used to discriminate between no injection (baseline) and IL-1β or TNF injection. (B and C) Illustrative example of the transformation of the data from the time domain to the CAP response domain (B), where the decoder detects the two responding CAP clusters, thus grouping the response values into the three distinct classes, baseline or IL-1β or TNF injection, using threefold cross-validation (C, Left). (C, Right) The concatenated out-of-sample prediction of the algorithm from all the folds to validate our algorithm shows the result of the decoding and is indicative of its accuracy.