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. 2018 Mar 12;4(5):187–190. doi: 10.1016/j.hrcr.2018.01.010

Figure 2.

Figure 2

Electrophysiological characteristics of SCN1B. A: Representative traces of sodium current with Nav1.5 alone, β1 subunit WT, β1B subunit WT, and β1B subunit p.R225C in HEK293 cells. B: Sodium current density for Nav1.5 alone, β1 subunit WT, β1B subunit WT, and β1B subunit p.R225C. C: Voltage dependence of steady-state activation for Nav1.5 alone, β1 subunit WT, β1B subunit WT, and β1B subunit p.R225C. D: Voltage dependence of steady-state inactivation for Nav1.5 alone, β1 subunit WT, β1B subunit WT, and β1B subunit p.R225C. In B, C, and D data points represent mean ± standard error of the mean. ∗P < .05 and ∗∗P < .01, based on a paired 2-tailed Student t test.