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. 2018 Mar 12;4(5):187–190. doi: 10.1016/j.hrcr.2018.01.010

Table 1.

Parameters for Na+-current density, activation, and inactivation

Current density (pA/pF)
Steady-state activation (SSA)
Steady-state inactivation (SSI)
n n V1/2 (mV) k n V1/2 (mV) k
Nav1.5 alone 10 −57.94 ± 19.34 13 −22.70 ± 0.77 5.43 ± 0.17 12 −68.06 ± 0.65 4.90 ± 0.19
Nav1.5 + β1 WT 19 −67.11 ± 10.04 12 −23.90 ± 1.37 5.64 ± 0.19 14 −68.94 ± 0.59 4.78 ± 0.11
Nav1.5 + β1B WT 17 −106.21 ± 11.71 10 −23.83 ± 1.29 5.08 ± 0.17 13 −65.50 ± 0.54 4.59 ± 0.14
Nav1.5 + β1B R225C 23 −111.41 ± 9.04 5 −24.19 ± 0.69 5.32 ± 0.13 20 −68.52 ± 0.52 4.77 ± 0.15

k = slope; n = number of recordings; V1/2 = voltage of half-maximal activation/inactivation.

P < .05 vs Nav1.5 alone, compared by paired 2-tailed Student t test.