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. 2018 Jun 1;9(42):26659–26669. doi: 10.18632/oncotarget.25426

Figure 2. Metastatic melanoma lesions presenting CD73 staining in tumor cells.

Figure 2

(A) Melanoma metastasis presenting 5–25% of tumor cells (TC) staining (arrows), with an intensity of 1 and a cytoplasmic pattern. (B) Metastatic melanoma with ≤5% of TC staining, with moderate to strong intensity (averaged to 2.5) and a membrane pattern (arrows). (C) Metastatic melanoma with 75–90% of TC staining, intensity 2 to 3, mixed pattern (membrane and cytoplasmic staining). Surrounding stromal tissue is mostly unstained (*). (D) Metastatic melanoma with ≥90% of TC homogeneously staining, with strong intensity (3) and a membrane pattern. Surrounding stromal tissue is mostly unstained (*).