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. 2018 Jun 1;9(42):26605–26615. doi: 10.18632/oncotarget.24902

Figure 7. Evaluation of cellular uptake of doxorubicin.

Figure 7

Confocal microscopy images of CD19-positive Ramos cells and CD19-negative Jurkat cells treated with free Dox (upper panel) or Apt-Dox (lower panel). Free doxorubicin emits a red fluorescence. In the lower panel, the red fluorescence was presumably from free doxorubicin released from Apt-Dox, which was taken up by the cells and digested. The nuclei were stained blue with DAPI.