Figure 8. Internalization of Apt-Dox by CD19-positive cells at 37°C and 4°C.

Ramos lymphoma cells were incubated with Apt-Dox for 2h at 37°C and 4°C, respectively. Confocal microscopy was applied to obtain the cellular images. The red fluorescence was emitted by doxorubicin. The nuclei were stained blue with DAPI.