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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Proteomics. 2018 Mar 14;18(12):e1700246. doi: 10.1002/pmic.201700246

Table I. Putative HLA DR-derived peptide sequences identified from plasma of four donors (D1-D4).

Uniprot Accession Protein Name Gene Name Aligned Peptide Sequence D1  D2  D3  D4 Collado1 Ciudad2 Maver-1 DOHH2
P01023 Alpha-2-macroglobulin A2M SSKFQVDNNNRLL                      X Donor A, B (DRB1*03:01)
P01833 Polymeric immunoglobulin receptor PIGR ASVDSGSSEEQGGSSRA
–SVDSGSSEEQGGSSRA 		        X
        X
P02808 Statherin STATH DSSEEKFL–
DSSEEKFLR 		        X
        X
P04406 Glyceraldehyde-3-phosphate dehydrogenase GAPDH GKVKVGVNGFGRIGR–
GKVKVGVNGFGRIGRL 		        X     X
                     X		 X
P05186 Alkaline phosphatase, tissue-nonspecific isozyme ALPL AHNNYQAQSAVPLRHE                X t1 (DRB1*01:01)
P06280 Alpha-galactosidase A GLA GPRSYTIAVASLGKG                X Donor D (DRB1*01:01) X X
P07339 Cathepsin D CTSD YTVFDRDNNRVGFAEAAR         X    X X
P07355 Annexin A2 ANXA2 RDALNIETAIKTKG                X Donor D (DRB1*01:01) X
P11279 Lysosome-associated membrane glycoprotein 1 LAMP1 LNTILPDARDPAFK                      X Donor A, B (DRB1*03:01)
P17936 Insulin-like growth factor-binding protein 3 IGFBP3 HSKIIIIKKGHAKD– –

HSKIIIIKKGHAKDSQ 		                     X

        X          X		 t4 (DRB1*03:01)
P21333 Filamin-A FLNA EETVITVDTKAAGKGK


–ETVITVDTKAAGKGK 		                     X

                     X		 Donor A (DRB1*03:01, DRB1*11:01)
P61769 Beta-2-microglobulin B2M RTPKIQVYSRHPAENGK
–TPKIQVYSRHPAE– – –
–TPKIQVYSRHPAEN– –

–TPKIQVYSRHPAENGK 		               X
               X

               X

               X


t5 (DRB1*11:04)
Donor B (DRB1*01:01)		                X
               X

               X

               X
Q02413 Desmoglein-1 DSG1 VATDLDTGRPSTTVR–
VATDLDTGRPSTTVRY 		        X
        X
Q9H3G5 Probable serine carboxypeptidase CPVL CPVL AGKYVPAIAHLIH–
AGKYVPAIAHLIHS

– –KYVPAIAHLIH–

– –KYVPAIAHLIHS 		               X
               X

               X

               X
t1 (DRB1*01:01)


t2 (DRB1*01:01)

Donor G (DRB1*07:01, DRB1*15:01) Multiple Donors




X
1

Peptide sequence identified by Collado et al. [39]

2

Peptide sequence identified by Ciudad et al. [40]