Fig. 8. Sensitivity of HCT-116 cells [parental cells (p53+/+) and its p53-null derivative (p53–/–)] to the treatment with compounds I and VI. DNA quantification of total cells after treatment with compound I (a) and VI (b) assessed as a measure of fluorescence of Sybr Green I. DNA contents of control, untreated cells were taken as 100%. The error bars represent the SDs, experiments were done in triplicate. (*) Denotes significant (P < 0.05) difference from p53-wild-type (p53+/+) cells.
