Table 1. IC₅₀ values (μM) of the compounds ^a .

	A2780	A2780cisR	MCF-7	A549	HCT-15	PC3	A498	BxPC3	A375
CDDP	2.8 ± 0.2	13.8 ± 0.2	17.4 ± 0.2	8.35 ± 0.87	11.32 ± 1.06	2.25 ± 0.82	17.53 ± 1.21	11.36 ± 1.14	4.03 ± 0.95
OXP	0.52 ± 0.27	4.2 ± 1.6	3.36 ± 0.2	1.46 ± 0.31	1.15 ± 0.43	5.24 ± 0.86	7.94 ± 1.04	4.15 ± 0.93	6.30 ± 1.11
I	0.25 ± 0.09	0.30 ± 0.10	0.91 ± 0.30	1.12 ± 0.32	0.81 ± 0.12	2.13 ± 0.45	2.43 ± 0.72	1.13 ± 0.14	1.25 ± 0.25
II	1.02 ± 0.6	1.62 ± 0.30	5.74 ± 1.10	8.36 ± 1.14	6.36 ± 1.03	7.32 ± 1.24	4.21 ± 0.95	3.54 ± 0.66	2.17 ± 0.53
III	1.3 ± 0.2	8.8 ± 2.1	5.7 ± 0.9	20.5 ± 2.14	16.4 ± 1.63	10.1 ± 1.17	5.21 ± 1.10	14.4 ± 2.16	4.17 ± 0.87
IV	5.4 ± 0.2	16.1 ± 0.7	31.6 ± 2.1	60.3 ± 3.34	51.5 ± 3.26	53.2 ± 4.24	21.1 ± 3.07	19.8 ± 2.25	47.3 ± 2.53
V	1.18 ± 0.33	1.29 ± 0.29	8.80 ± 1.48	15.5 ± 1.13	14.4 ± 2.05	16.8 ± 1.41	8.64 ± 0.95	4.43 ± 1.94	12.4 ± 2.93
VI	0.14 ± 0.03	0.12 ± 0.03	0.18 ± 0.03	0.17 ± 0.04	0.31 ± 0.04	0.41 ± 0.06	0.43 ± 0.02	0.19 ± 0.01	0.16 ± 0.02
VII	0.65 ± 0.04	1.54 ± 0.27	3.43 ± 0.14	7.16 ± 1.11	5.17 ± 0.85	4.34 ± 1.25	8.42 ± 1.47	10.14 ± 1.69	6.25 ± 1.94
VIII	0.90 ± 0.08	1.96 ± 0.44	2.28 ± 0.46	19.63 ± 3.22	12.54 ± 1.13	6.35 ± 1.19	9.32 ± 1.07	7.64 ± 1.15	0.64 ± 0.13
IX	—	—	11.52 ± 3.71	22.52 ± 4.54	15.34 ± 3.23	2.98 ± 1.35	21.98 ± 0.85	6.23 ± 1.47	1.93 ± 0.75
X	—	—	19.88 ± 1.41	26.14 ± 2.89	18.89 ± 3.18	5.85 ± 1.08	24.36 ± 5.35	14.33 ± 2.09	6.85 ± 1.55
XI	—	—	39.52 ± 4.45	32.32 ± 4.25	40.23 ± 2.86	10.11 ± 2.02	20.12 ± 0.85	36.59 ± 3.39	29.69 ± 5.16
XII	—	—	46.58 ± 1.48	35.14 ± 4.25	48.28 ± 3.33	15.85 ± 2.87	22.45 ± 5.05	29.69 ± 5.16	19.59 ± 2.84
PhB	—	—	1735 ± 27	1989 ± 22	1214 ± 81	795 ± 18	925 ± 81	1523 ± 36	25.65 ± 2.89

^aAn average of three measurements.