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. 2016 Jan 15;7(3):2381–2391. doi: 10.1039/c5sc04205d

Table 2. log P (octanol/water) values obtained by shake flask method a .

Compound Formula log P
Cisplatin26 –2.25 ± 0.04
I ctc-[Pt(NH3)2(VPA)2Cl2]26 0.25 ± 0.03
II ctc-[Pt(NH3)2(Ac)(VPA)Cl2]26 0.17 ± 0.02
III [Pt(DACH)(VPA)2(ox)]25 0.37 ± 0.08
IV [Pt(DACH)(VPA)(OH)(ox)]25 0.10 ± 0.05
VI ctc-[Pt(NH3)2(PhB)2Cl2] –0.73 ± 0.05
VIII [Pt(DACH)(PhB)2(ox)] 0.25 ± 0.02

aResults are expressed as the mean ± SD from three independent experiments.