Table 3. Cytotoxicity [IC₅₀ mean values (μM)] obtained for compounds I and VI in the isogenic HCT-116 cells [parental cells (p53^+/+) and its p53-null derivative (p53^–/–)] ^a .

	HCT-116+/+	HCT-116–/–
I	0.46 ± 0.07	1.4 ± 0.2
VI	0.22 ± 0.03	0.34 ± 0.08

^aResults are expressed as the mean ± SD from three independent experiments.