Table 4.
Outcomes at 1 year.
Unadjusted | Adjusted | |||
---|---|---|---|---|
Adverse employment change (n=492) | No adverse change (n=4238) | P value | HR (95% CI) | |
PHQ2 depression score >3 | 27.4% | 16.7% | <0.001 | 1.60 (1.27, 2.02) |
EQ5D Visual Analog Scale | 73 (17.8) | 78 (14.8) | <0.001 | −3.23 (−4.73, −1.74)* |
Medication adherence | 68.0% | 70.6% | 0.226 | 1.15 (0.93, 1.41) |
Medication persistence | ||||
• P2Y12 inhibitors | 86.1% | 88.2% | 0.185 | 0.88 (0.68, 1.14) |
• Aspirin | 95.3% | 96.3% | 0.239 | 0.86 (0.53, 1.40) |
• Statins | 86.1% | 88.3% | 0.178 | 0.87 (0.67, 1.13) |
• Beta-blockers | 86.0% | 87.0% | 0.565 | 0.91 (0.70, 1.17) |
• ACEi/ARB | 78.0 | 81.4% | 0.116 | 0.80 (0.63, 1.02) |
Moderate/extreme financial hardship with medication costs | 41.0% | 28.4% | <0.001 | 1.57 (1.33, 1.87) |
Continuous variables expressed as mean (standard deviation). Adjusted for age, sex, race, BMI, MI type, prior MI, diabetes, hypertension, smoking, unplanned rehospitalizations in first year, BARC 2+ bleeding in first year, number of medications reported at 1 year, baseline EQ5D VAS, baseline PHQ2. *Linear regression results expressed as estimate (95% CI)
Abbreviations: ACEi – angiotensin converting enzymes inhibitor, ARB – angiotensin receptor blocker, CI – confidence interval, HR – hazard ratio