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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Circ Cardiovasc Qual Outcomes. 2018 Jun;11(6):e004528. doi: 10.1161/CIRCOUTCOMES.117.004528

Table 4.

Outcomes at 1 year.

Unadjusted Adjusted
Adverse employment change (n=492) No adverse change (n=4238) P value HR (95% CI)
PHQ2 depression score >3 27.4% 16.7% <0.001 1.60 (1.27, 2.02)
EQ5D Visual Analog Scale 73 (17.8) 78 (14.8) <0.001 −3.23 (−4.73, −1.74)*
Medication adherence 68.0% 70.6% 0.226 1.15 (0.93, 1.41)
Medication persistence
 • P2Y12 inhibitors 86.1% 88.2% 0.185 0.88 (0.68, 1.14)
 • Aspirin 95.3% 96.3% 0.239 0.86 (0.53, 1.40)
 • Statins 86.1% 88.3% 0.178 0.87 (0.67, 1.13)
 • Beta-blockers 86.0% 87.0% 0.565 0.91 (0.70, 1.17)
 • ACEi/ARB 78.0 81.4% 0.116 0.80 (0.63, 1.02)
Moderate/extreme financial hardship with medication costs 41.0% 28.4% <0.001 1.57 (1.33, 1.87)

Continuous variables expressed as mean (standard deviation). Adjusted for age, sex, race, BMI, MI type, prior MI, diabetes, hypertension, smoking, unplanned rehospitalizations in first year, BARC 2+ bleeding in first year, number of medications reported at 1 year, baseline EQ5D VAS, baseline PHQ2. *Linear regression results expressed as estimate (95% CI)

Abbreviations: ACEi – angiotensin converting enzymes inhibitor, ARB – angiotensin receptor blocker, CI – confidence interval, HR – hazard ratio