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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Psychoneuroendocrinology. 2018 May 21;94:143–151. doi: 10.1016/j.psyneuen.2018.05.012

Figure 3.

Figure 3

Pharmacological inhibition of IL-6 prior to extinction training improves retention of fear memory extinction. a Study design. b Conditioned freezing in response to 12 CS following four days of Ab treatment. c Testing for retention of fear memory extinction one day after extinction training. d Total average conditioned freezing in response to four CS during extinction training (Day 5) and testing (Day 6). e Total average conditioned freezing in response to four CS during extinction training and testing in mice treated with only two doses of ControlAb or IL6Ab prior to extinction training. (n=10/group) *P<0.05, ^P<0.01, #P<0.001.