Table 3.
Adjusted analyses for PET measures of myocardial flow and the primary outcome.
| Myocardial Flow Reserve (MFR) | |||
|---|---|---|---|
| Covariates | Hazard Ratio (95% CI) |
χ2 | P Value |
| MFR + rest EF | 0.31 (0.13-0.76) | 23.58 | 0.010 |
| MFR + SSS | 0.36 (0.15-0.86) | 27.35 | 0.021 |
| MFR + SDS | 0.27 (0.11-0.64) | 18.51 | 0.003 |
| MFR + SRS | 0.26 (0.11-0.60) | 20.75 | 0.002 |
| MFR + Time since OHT | 0.23 (0.10-0.53) | 16.76 | <0.001 |
| MFR + Prior Diagnosis of CAV* | 0.20 (0.07-0.58) | 9.97 | 0.003 |
| Stress Myocardial Blood Flow (Stress MBF) | |||
| Covariates |
Hazard Ratio (95% CI) |
χ2 | P Value |
| Stress MBF + rest EF | 0.67 (0.38-1.18) | 19.59 | 0.165 |
| Stress MBF + SSS | 0.68 (0.40-1.16) | 24.37 | 0.155 |
| Stress MBF + SDS | 0.54 (0.32-0.92) | 14.55 | 0.023 |
| Stress MBF + SRS | 0.56 (0.34-0.91) | 16.77 | 0.020 |
| Stress MBF + Time since OHT | 0.52 (0.30-0.88) | 9.50 | 0.015 |
| Stress MBF + Prior Diagnosis of CAV* | 0.51 (0.27-0.96) | 5.84 | 0.037 |
EF indicates left ventricular ejection fraction; SSS, summed stress score; SDS, summed difference score; SRS, summed rest score; OHT, orthotopic heart transplantation; CAV, cardiac allograft vasculopathy.
*
Analyses included 62 patients as 55 patients did not have angiography available. Of the 62 patients, 21 patients had a prior diagnosis of CAV. The primary outcome was observed in 17 of 62 patients.