Fig. 6.
CD4 T cell infiltration in the CNS is greater in MV-infected adults than in neonates.
Whole brain homogenates from neonatal and adult CD46+ (A) and CD46+/IFNγ-KO (B) mice were analyzed for infiltrating T cells at 7 dpi. Flow cytometry was performed for CD4 T cells (CD3+/CD4+/CD19−) or CD8 T cells (CD3+/CD8+/CD19−). Mice from 4 to 5 different litters were compared for each condition. Statistical analysis was applied by two-way ANOVA (*p < 0.05) with Bonferroni post hoc test.