Table 5.
Protein | Day 1 (n=134) | Day 7 (n=136) | Day 14 (n=128) | |||||||
---|---|---|---|---|---|---|---|---|---|---|
BMI centile at24 months | ||||||||||
< 85 | 85-94 | ≥ 95 | < 85 | 85-94 | ≥ 95 | < 85 | 85-94 | ≥ 95 | ||
Systemic inflammation | CRP | 20 | 0 | 8 | 47 | 14 | 33 | 39 | 50 | 44 |
SAA | 24 | 0 | 8 | 38 | 43 | 17 | 32 | 25 | 22 | |
MPO | 10 | 13 | 8 | 14 | 14 | 17 | 27 | 13 | 56 | |
Cytokines and receptors | IL-1β | 15 | 13 | 8 | 22 | 43 | 33 | 35 | 38 | 67 |
IL-6 | 15 | 0 | 0 | 62 | 29 | 33 | 35 | 25 | 56 | |
IL-6R | 18 | 25 | 0 | 22 | 0 | 33 | 30 | 0 | 33 | |
TNF-α | 16 | 13 | 0 | 26 | 29 | 29 | 36 | 25 | 67 | |
TNF-R1 | 13 | 0 | 0 | 29 | 14 | 17 | 31 | 38 | 33 | |
TNF-R2 | 15 | 13 | 0 | 33 | 14 | 17 | 32 | 13 | 22 | |
Chemokines | IL-8 | 23 | 13 | 0 | 22 | 14 | 8 | 37 | 13 | 56 |
MCP-1 | 28 | 13 | 25 | 32 | 14 | 25 | 37 | 25 | 33 | |
MCP-4 | 23 | 25 | 17 | 28 | 14 | 17 | 31 | 38 | 22 | |
MIP-1β | 16 | 25 | 8 | 26 | 14 | 8 | 31 | 38 | 22 | |
RANTES | 18 | 13 | 0 | 15 | 0 | 8 | 25 | 38 | 0 | |
I-TAC | 19 | 25 | 8 | 28 | 43 | 17 | 22 | 50 | 22 | |
Adhesion molecules | ICAM-1 | 20 | 0 | 0 | 46 | 0 | 33 | 43 | 0 | 33 |
ICAM-3 | 10 | 13 | 8 | 10 | 14 | 0 | 29 | 25 | 33 | |
VCAM-1 | 19 | 13 | 0 | 17 | 0 | 33 | 20 | 13 | 33 | |
E-SEL | 15 | 0 | 0 | 26 | 0 | 17 | 32 | 50 | 11 | |
Matrix metallo-proteinases | MMP-1 | 17 | 0 | 8 | 20 | 0 | 33 | 19 | 25 | 11 |
MMP-9 | 9 | 13 | 8 | 8 | 14 | 17 | 28 | 13 | 44 | |
Angiogenic proteins | VEGF | 9 | 13 | 0 | 8 | 14 | 8 | 22 | 63 | 22 |
VEGF-R1 | 49 | 25 | 25 | 21 | 29 | 33 | 25 | 63 | 44 | |
VEGF-R2 | 20 | 0 | 0 | 32 | 0 | 8 | 41 | 13 | 11 | |
IGFBP-1 | 50 | 50 | 25 | 41 | 57 | 33 | 36 | 25 | 22 | |
Maximum number of infants | 114 | 8 | 12 | 117 | 7 | 12 | 111 | 8 | 9 |