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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Traffic. 2018 May 11;19(7):496–502. doi: 10.1111/tra.12571

Figure 2. Proposed roles of mRNA localized to centrosomes.

Figure 2

While the exact function of mRNA localized to centrosomes remains unknown, several models have been proposed. Note that these models of RNA function at centrosomes are non-exclusive. (A) RNA localization to centrosomes may regulate centrosome biology through translational regulation. Centrosome localization may represent a translationally permissive or inhibitory environment. Alternatively, RNA localization may sequester transcripts away from the cytosolic translational machinery. (B) RNA localization may contribute to centrosome structure, such as through the formation of a phase separated condensate. (C) The asymmetric distribution of centrosome-localized RNAs may regulate asymmetric cell divisions.