Table 2.
Repeatability of multiparametric MRI.
| cT1 | T2* | PDFF | |
|---|---|---|---|
| Scan-Rescan | |||
| Mean CoV (%) | 2·1 | 2·6 | 8·8 |
| Pearson’s r (95% CI) | 0·73 (0·19–0·93) | 0·99 (0·97–1·0) | 0·99 (0·96 to 1·0) |
| Bland-Altman Analysis‡ | |||
| Bias (mean (±SD)) | −13 (35) | −0·05 (0·83) | −1·1 (2·3) |
| p-value † | 0·285 | 0·862 | 0·250 |
| 95% limits of agreement | −81 to 56 | −1·7 to 1·6 | −5·7 to 3·5 |
| 10 week time course | |||
| Mean CoV (%) | 2·8 | 6·6 | NA# |
| Fasted-Fed | |||
| Mean CoV (%) | 1·40 | 7·4 | NA## |
| Pearson’s r (95% CI) | 0·94 (0·82–0·98) | 0·90 (0·71–0·97) | |
| Bland-Altman Analysis | |||
| Bias (mean±SD) | −3 (22) | 1·4 (2·9) | |
| p-value† | 0·606 | 0·070 | |
| 95% limits of agreement | −46 to 40 | −4·2 to 7·1 | |
#All healthy volunteers had PDFF of < 2%; ##only 2 healthy volunteers had PDFF > 2%. †From a paired t-test, to test for significant bias. ‡See Supplementary Fig. 1 for B-A plots.