Table 3.
Association of variables with eGFR
| Variable | Univariate regression | Multivariate regression | ||
|---|---|---|---|---|
| B coefficient (SE) | P | B coefficient (SE) | P | |
| Age, months | 0.524 (0.025) | < 0.001 | ||
| Body weight, kg | 1.129 (0.067) | < 0.001 | ||
| Gender | −0.063 (0.062) | 0.317 | ||
| PRISM III score | 0.000 (0.006) | 0.959 | ||
| MV | −0.033 (0.063) | 0.595 | ||
| Duration of MV, hours | 0.000 (0.000) | 0.302 | ||
| sFGF23, pg/mL | −0.842 (0.108) | < 0.001 | −0.156 (0.075)a | 0.040 |
| sIGFBP-7, ng/mL | −0.657(0.214) | 0.003 | −0.111 (0.113)a | 0.327 |
| sCysC, mg/L | −1.062 (0.113) | < 0.001 | −0.702 (0.048)a | < 0.001 |
| uFGF23, pg/mg uCr | −0.169 (0.051) | 0.001 | −0.050 (0.027)a | 0.061 |
| uIGFBP-7, ng/mg uCr | −0.013 (0.065) | 0.843 | ||
| uCysC, ng/mg uCr | −0.097 (0.042) | 0.022 | −0.067 (0.020)a | 0.001 |
eGFR estimated glomerular filtration rate, MV mechanical ventilation, PRISM III pediatric risk of mortality III. eGFR was calculated based on age, body weight, and serum levels of creatinine and cystatin C
aAfter adjustment for age and body weight. All continuous variables were log-transformed