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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Lung Cancer. 2018 May 1;121:82–90. doi: 10.1016/j.lungcan.2018.04.024

Fig. 1. Downregulation of HIF-1α and c-Jun protein correlates with cell inhibitory response to gefitinib treatment in NSCLC cells.

Fig. 1

A. HCC827 and H3255 cells (left panel) and H1650 and H1975 cells (right panel) were treated with the indicated concentrations of gefitinib for 5 days. Cell survival was measured by MTT proliferation assay. B. HCC827, H3255, H1650, and H1975 cells were treated with the indicated concentrations of gefitinib for 24 hours. Cells were then harvested, and equal amounts of protein lysates were subjected to Western blot analysis with the indicated antibodies. The level of β-actin was used as a reference of lysate protein loading control of each cell line.