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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Hypertension. 2018 May 29;72(1):235–246. doi: 10.1161/HYPERTENSIONAHA.118.10824

Figure 4. ER stress is involved in ROS generation in SHR VSMCs.

Figure 4

ROS generation was measured by chemiluminescence (A) and amplex red (B) in the presence of the chemical chaperone 4-PBA (1mmol/L, 24h). Nox1 (C) and Nox4 (D) expression in the presence of 4-PBA was assessed by western blot. Protein quantification was normalized by α- tubulin. Results are expressed as mean±SEM of 6-9 separate experiments. *p<0.05 vs WKY Ctl, and +p<0.05 vs SHR Ctl.