Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Hypertension. 2018 May 29;72(1):235–246. doi: 10.1161/HYPERTENSIONAHA.118.10824

Figure 6. ER stress is involved in increased proliferation in VSMCs from SHR.

Figure 6

(A) Spliced XBP1 expression (sXBP1) was detected by western blot in VSMCs from WKY and SHR in the presence of Nox inhibitors (NoxA1ds or GKT137831) and ER stress inhibitors (4-PBA). Protein quantification was normalized by α- tubulin. Proliferation was assessed using the CSFE assay (B and C) in the presence of Nox inhibitors, ER stress inhibitor and IRE1 inhibitor STF-083010 (STF). Results are expressed as mean±SEM of 5 separate experiments. *p<0.05 vs WKY Ctl and and +p<0.05 vs SHR Ctl.