Figure 5. High BDNF expression and tumor nerve counts correlate with poor outcome in ovarian cancer patients.
(a) BDNF expression in human ovarian tumors and Kaplan-Meier curves of disease-specific survival in patients with epithelial ovarian carcinoma (n = 108) with high or low BDNF expression. (b) Nerve counts in human ovarian tumors and Kaplan-Meier curves of disease-specific survival in patients with epithelial ovarian carcinoma (n = 108) with high or low nerve counts. (c–d) Correlation of intratumoral NE levels in human ovarian tumor samples with BNDF and nerve counts. Scale bar represents 50 μM.