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. Author manuscript; available in PMC: 2019 Jun 15.
Published in final edited form as: Cancer Res. 2018 Apr 16;78(12):3176–3189. doi: 10.1158/0008-5472.CAN-17-3470

Figure 1.

Figure 1

ERβ5 is highly expressed in GBM. Expression of ERβ isoforms was determined by isoform specific RT-qPCR primers using patient-derived GBM cells (A) and established GBM cells (B). ERβ isoforms expression was examined using isoform specific RT-qPCR primers in patient GBM specimens (n=18) (C). A glioma tissue microarray containing control brain (n=16), as well as grade II (n=130), grade III (n=29) and grade IV (n=33) glioma specimens was used to determine ERβ5 expression using immunohistochemistry (D). Quantitation of total score in each grade was done as described in methods section. Data are represented as mean ± SE. * p<0.05; ** p<0.01; *** p<0.001. ns= non significant.