Table 2.
Medial temporal volumetric measures of the SCD, MCI and HC groups.
| SCD | MCI | Control | F | ANCOVA | |||
|---|---|---|---|---|---|---|---|
| (n = 111) | (n = 30) | (n = 67) | HC vs. SCD | HC vs. MCI | SCD vs. MCI | ||
| Brain size index | 0.80 ± 0.09 | 0.80 ± 0.07 | 0.81 ± 0.08 | n.s. | |||
| HIPPOCAMPUS | |||||||
| Left | 2.33 ± 0.86 | 2.18 ± 0.28 | 2.42 ± 0.27 | 8.44** | NS | HC>MCI** | NS |
| Right | 2.52 ± 0.32 | 2.28 ± 0.34 | 2.66 ± 0.29 | 17.78** | HC>SCD* | HC>MCI** | SCD>MCI* |
| Asymmetry (%) | 3.98 ± 3.31 | 2.19 ± 4.07 | 5.08 ± 4.31 | 6.076* | NS | HC>MCI* | NS |
| AMYGDALA | |||||||
| Left | 1.74 ± 0.24 | 1.62 ± 0.20 | 1.80 ± 0.25 | 5.92* | NS | HC>MCI* | NS |
| Right | 1.47 ± 0.20 | 1.32 ± 0.23* | 1.56 ± 0.20 | 16.91** | HC>SCD* | HC>MCI** | SCD>MCI* |
| Asymmetry (%) | −8.41 ± 5.98 | −10.49 ± 5.75* | −6.88 ± 4.11 | 4.785* | NS | HC>MCI* | NS |
| TEMPORAL HORN | |||||||
| Left | 0.69 ± 0.14 | 0.73 ± 0.27 | 0.69 ± 0.13 | NS# | |||
| Right | 0.55 ± 0.16 | 0.62 ± 0.24 | 0.53 ± 0.12 | NS# | |||
| Asymmetry (%) | −11.78 ± 11.19 | −10.04 ± 10.27 | −13.20 ± 10.06 | NS | |||
Asymmetry is defined as [right volume-left volume]/[total volume]*100%; Post-hoc was Bonferroni corrected (p < 0.05/3 = 0.017); the regional MRI data were adjusted for brain size index; #Kruskal-Wallis test was used (unadjusted). Symbol: NS denotes non-significant.