Table 3.
SCD vs. HC | MCI vs. HC | SCD vs. MCI | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | |||||||
OR (95%CI) | p | OR (95%CI) | p | OR (95%CI) | p | OR (95%CI) | p | OR (95%CI) | p | OR (95%CI) | p | |
Right hippocampus | 0.15(0.38–0.56) | 0.005 | 0.09(0.02–0.39) | 0.001 | 0.35(0.00–0.57) | 0.019 | 0.02(0.00–0.98) | 0.049 | 0.46(0.08–2.64) | 0.386 | 0.73(0.10–5.37) | 0.756 |
Asymmetry of hippocampus | 0.92(0.84–1.01) | 0.07 | 0.92(0.84–1.01) | 0.07 | 0.79(0.66–0.95) | 0.012 | 0.75(0.58–0.97) | 0.030 | 0.86(0.75–0.99) | 0.037 | 0.88(0.75–1.02) | 0.087 |
Right amygdala | 0.07(0.01–0.55) | 0.012 | 0.04(0.01–0.38) | 0.005 | 0.01(0.00–0.72) | 0.035 | 0.004(0.00–1.12) | 0.055 | 0.19(0.01–3.55) | 0.265 | 0.66(0.02–19.15) | 0.809 |
Asymmetry of amygdala | 0.93(0.88–1.00) | 0.035 | 0.93(0.87–0.99) | 0.035 | 0.84(0.73–0.96) | 0.009 | 0.77(0.63–0.93) | 0.008 | 0.92(0.85–1.00) | 0.051 | 0.94(0.86–1.02) | 0.146 |
Significant coefficients and p-values are in bold font (p < 0.05). Model 1 was adjusted for gender, age, years of education and brain size index; Model 2 was additionally adjusted for GDS score, self-reported anxiety, hypertension, hyperlipidemia, diabetes mellitus, heart disease and lifestyle of smoking.