Table 1.
Parameter estimate under the null | Gaussian ATOMM estimate (SE) | Binomial-like ATOMM estimate (SE) |
Intercept, | 0.19 (0.011) | -0.75 (0.013) |
Person 1, | 0.15 (0.015) | 0.16 (0.015) |
Person 2, | 0.20 (0.015) | 0.19 (0.015) |
Total residual variance, | 1.23 | 1.45 |
Proportion of residual variance due to | ||
A. thaliana, | 0.021 | 0.011 |
X. arboricola, | 0.441 | 0.581 |
A. thaliana–X. arboricola interaction, | 0.048 | 0.011 |
Plant/block effect, | 0.093 | 0.069 |
We included in ATOMM the person effects (i.e., effects due to which lab researcher scored the QDR) as covariates. There were three persons measuring the trait scores. One person effect is subsumed into the intercept, leaving us to estimate effects of person 1 and person 2 only. In addition to the four genetic VCs described in Eq. 3, we also included the plant effect as arandom effect (see Materials and Methods). The parameters were estimated under the global null hypothesis .