Fig. 5.

Stability measurements for 10 experimentally characterized synthetic collagen peptide heterotrimer systems were taken from various studies (18, 37, 39). Corresponding predicted stabilities were calculated by using Eq. 1 and the original scoring function used to design abc (18, 35). Where registry of a heterotrimer was not determined, the most stable computed association state was assumed. A detailed breakdown of favorable and unfavorable electrostatic interactions is presented in SI Appendix, Table S5.