Table 2.

Effects of charge reversals on stability

Interaction	Location	Tm, °C	ΔTm, °C*
Lateral DD	b:D16 c:K15D	28.2	−2.6
Lateral KK	c:D10K a:K12	30.0	−1.3
	c:K19 a:D21K	33.4	−1.0
Axial DD	a:D16 b:K18D	29.0	−4.5
Axial KK	c:D7K a:K12	34.4	−0.6
	c:K19 a:D24K	29.3	−1.9

Isolated charge-pair networks are highlighted in bold.

^*$\mathrm{\Delta }{T}_m=T_{m,\hspace{0.17em}Repulsion.}-T_{m,Ala.}$ Corresponding $T_{m,Ala.}$ values are in Table 1.