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. 2018 May 29;115(24):6261–6266. doi: 10.1073/pnas.1802212115

Table 1.

Discovery stage to identify SNPs associated with choroidal thickness

SNP CHR Position Effect allele EAF Nearby genes Discovery stage Replication stage Meta-analysis
N β P N β P N β P
rs3753394 1 196620917 C 0.487 CFH (nearby) 3,418 11.84 2.44 × 10−8
rs800292 1 196642233 A 0.406 CFH (in gene) 3,418 11.55 8.43 × 10−8 2,692 8.61 4.37 × 10−4 6,110 10.27 2.05 × 10−10
rs7782658 7 158858007 A 0.307 VIPR2 (in gene) 3,418 11.59 4.03 × 10−7
rs3793217 7 158848821 G 0.213 VIPR2 (in gene) 3,418 12.46 1.28 × 10−6 2,692 7.69 7.58 × 10−3 6,110 10.34 6.75 × 10−8

CHR, chromosome; EAF, effect allele frequency in the discovery stage.