Table 1.
SNP | CHR | Position | Effect allele | EAF | Nearby genes | Discovery stage | Replication stage | Meta-analysis | ||||||
N | β | P | N | β | P | N | β | P | ||||||
rs3753394 | 1 | 196620917 | C | 0.487 | CFH (nearby) | 3,418 | 11.84 | 2.44 × 10−8 | — | — | — | — | — | — |
rs800292 | 1 | 196642233 | A | 0.406 | CFH (in gene) | 3,418 | 11.55 | 8.43 × 10−8 | 2,692 | 8.61 | 4.37 × 10−4 | 6,110 | 10.27 | 2.05 × 10−10 |
rs7782658 | 7 | 158858007 | A | 0.307 | VIPR2 (in gene) | 3,418 | 11.59 | 4.03 × 10−7 | — | — | — | — | — | — |
rs3793217 | 7 | 158848821 | G | 0.213 | VIPR2 (in gene) | 3,418 | 12.46 | 1.28 × 10−6 | 2,692 | 7.69 | 7.58 × 10−3 | 6,110 | 10.34 | 6.75 × 10−8 |
CHR, chromosome; EAF, effect allele frequency in the discovery stage.