Table 3.

Comparison of the relative experimental rates, $k/k^{\mathrm{W}\mathrm{T}}$, to the those calculated while neglecting DA compression

Mutant	$k/k^{\mathrm{W}\mathrm{T}}$	$k_{\mathrm{A}}/k_{\mathrm{A}}^{\mathrm{W}\mathrm{T}}$	$k_{\mathrm{P}\mathrm{a}\mathrm{t}\mathrm{h}}/k_{\mathrm{P}\mathrm{a}\mathrm{t}\mathrm{h}}^{\mathrm{W}\mathrm{T}}$
WT	1.0	1.00	1.00
N47D	0.5(1)	0.64(1)	0.73(4)
N47S	0.23(5)	0.83(2)	0.75(5)
N47L	1.9(5)	0.93(2)	0.57(3)

$k_{\mathrm{A}}/k_{\mathrm{A}}^{\mathrm{W}\mathrm{T}}$ uses Eq. 6 for the electronic coupling, and $k_{\mathrm{P}\mathrm{a}\mathrm{t}\mathrm{h}}/k_{\mathrm{P}\mathrm{a}\mathrm{t}\mathrm{h}}^{\mathrm{W}\mathrm{T}}$ uses the Pathways model.