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. 2018 Jul;17(7):609–617. doi: 10.1016/S1474-4422(18)30167-4

Table 2.

Prevalence of RLS in patients with cryptogenic events compared with patients with events of known cause

Cryptogenic Known cause Odds ratio (95% CI) p value
RLS of any size
Age ≤60 years 29/74 (39%) 16/52 (31%) 1·45 (0·68–3·07) 0·33
Age >60 years 68/190 (36%) 44/207 (21%) 2·06 (1·32–3·23) 0·001
Total 97/264 (37%) 60/259 (23%) 1·93 (1·32–2·82) 0·001
Large RLS only
Age ≤60 years 16/74 (22%) 12/52 (23%) 0·92 (0·39–2·15) 0·85
Age >60 years 25/190 (13%) 15/207 (7%) 1·94 (0·99–3·80) 0·05
Total 41/264 (16%) 27/259 (10%) 1·58 (0·94–2·66) 0·08

Data are n/N (%) unless otherwise indicated. Data are stratified by age and size of the shunt. RLS=right-to-left shunt.