Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Values with standard deviation (SD) represent the average from at least three experiments.
RLM represents rat liver microsomal stability conducted at NCATS in the presence of NADPH.
Compounds noted as >57 μM represent a very weak or no inhibition [efficacy of ≤50% of full inhibition at highest tested concentration (57 μM)].
