Table 2. Additional SAR of N,N′-(1,2-Phenylene)dibenzenesulfonamide Derivatives.
compd | R1 | R2 | R3 | IC50 (μM) |
---|---|---|---|---|
7a | m-Cl | m-Cl | H | 5.7 |
7b | m-Cl | m-Cl | Me | 4.3 |
7c | m-Cl, p-Me | m-Cl, p-Me | H | 2.3 |
7d | m-Cl, p-Me | m-Cl, p-Me | F | 3.7 |
compd | R1 | R2 | R3 | IC50 (μM) |
---|---|---|---|---|
7a | m-Cl | m-Cl | H | 5.7 |
7b | m-Cl | m-Cl | Me | 4.3 |
7c | m-Cl, p-Me | m-Cl, p-Me | H | 2.3 |
7d | m-Cl, p-Me | m-Cl, p-Me | F | 3.7 |