Table II.
Group | Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 |
---|---|---|---|---|---|---|---|---|
Control | 85 ± 2.70 | 83 ± 1.41 | 80 ± 1.28 | 82 ± 0.81 | 81 ± 0.81 | 84 ± 1.28 | 80 ± 1.28 | 84 ± 1.28 |
Sham | 101 ± 1.63** | 102 ± 2.16** | 110 ± 2.94*** | 116 ± 2.22*** | 121 ± 2.51*** | 121 ± 2.44*** | 122 ± 2.15*** | 122 ± 2.1*** |
EXP-1 | 100 ± 1.82** | 105 ± 2.44** | 108 ± 1.63*** | 115 ± 2.08*** | 108 ± 0.81+ | 98 ± 1.72++ | 92 ± 1.82++ | 88 ± 1.28++ |
EXP-2 | 103 ± 2.70** | 106 ± 1.41** | 114 ± 0.41*** | 117 ± 0.81*** | 110 ± 0.81+ | 101 ± 1.28++ | 89 ± 1.41++ | 84 ± 1.28++ |
Metformin | 99 ± 1.41** | 103 ± 2.08** | 112 ± 2.39*** | 116 ± 1.63*** | 106 ± 0.81+ | 100 ± 1.82++ | 90 ± 1.63++ | 85±0.81++ |
Values are presented as mean ± SE (n=6/each group).
Sham: PCOS rats + i.p. injection of tween (80)
EXP-1: PCOS rats + i.p. injection of thymoquinone (8 mg/kg)
EXP-2: PCOS rats + i.p. injection of thymoquinone (16 mg/kg)
Statistically different from the control rats (p≤0.01),
statistically different from the control rats (p≤0.001),
statistically different from the sham rats (p≤0.05),
statistically different from the sham rats (p≤0.01).