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. Author manuscript; available in PMC: 2018 Nov 6.
Published in final edited form as: Mol Pharm. 2017 Oct 3;14(11):4042–4051. doi: 10.1021/acs.molpharmaceut.7b00710

Figure 2. HDL NPs modulate cholesterol biosynthesis gene expression.

Figure 2

(a) HDL NPs upregulate expression of DHCR7, LSS and SQLE in SUDHL4 cells but not TMD8 or HBL-1 cells. Human HDL does not impact expression of any gene in any cell line. *p<0.05 vs. PBS control. (b) Expression of DHCR7, LSS and SQLE was higher in TMD8 and HBL-1 cells compared with SUDHL4 cells.