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. Author manuscript; available in PMC: 2018 Nov 6.
Published in final edited form as: Mol Pharm. 2017 Oct 3;14(11):4042–4051. doi: 10.1021/acs.molpharmaceut.7b00710

Figure 6. Targeted cholesterol depletion and cell death induction in GC (top) and ABC DLBCL (bottom) mediated by HDL NPs.

Figure 6

Taken together, these molecular and functional studies clearly demonstrate the potential of targeted disruption of cellular cholesterol homeostasis in lymphoma, and provide a framework for further studies and novel therapeutic combinations, not only in lymphoma but other cholesterol-dependent malignancies.