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. 2018 Apr 27;15(6):9673–9680. doi: 10.3892/ol.2018.8592

Figure 2.

Figure 2.

Effect of 6-O-angeloylplenolin on MDR1, MRP1 and YBX1 mRNA level. Cells were treated with 6-O-angeloylplenolin for 12 h. RT-PCR analysis was applied to expression of MDR1, MRP1, and YBX1. (A) Electrophoresis gel image of RT-PCR products. (B) The ratio (to GAPDH) of in the cells treated with different concentrations of 6-O-angeloylplenolin by scanning densitometry (n=4). *P<0.05 and **P<0.01 vs. HCT-8/VCR cells; ||P<0.01 vs. untreated HCT-8 cells. RT-PCR, reverse transcription-polymerase chain reaction; MDR1, ATP-binding cassette sub-family B member 1; MRP1, ATP binding cassette subfamily C member 1; YBX1, Y-box binding protein 1.