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. 2018 Apr 27;15(6):9697–9702. doi: 10.3892/ol.2018.8601

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Copyright: © Xiao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — MPC1 is downregulated in U87 cells and upregulated by COUP-TFII suppression. (A) MPC1 mRNA expression was significantly decreased in U87 cells compared with normal brain cell line (HEB). *P<0.05 vs. the normal brain cell line. (B) COUP-TFII mRNA expression was significantly decreased by siCOUP-TFII in U87 cells compared with siNC and untreated cells. *P<0.05 vs. siNC and untreated group (C) MPC1 mRNA was significantly increased by siCOUP-TFII in U87 cells compared with siNC and untreated, *P<0.05 vs. siNC and untreated group as evaluated by a reverse transcription-quantitative polymerase chain reaction. COUP-TFII, chicken ovalbumin upstream promoter transcription factor II; MPC1, mitochondrial pyruvate carrier 1; NC, negative control; si, small-interfering.