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. 2018 Apr 27;15(6):9697–9702. doi: 10.3892/ol.2018.8601

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Copyright: © Xiao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Downregulation of COUP-TFII suppresses cell proliferation via targeting MPC1. (A) Luciferase activity was significantly reduced in U87 cells that were infected with siCOUP-TFII compared with untreated cells or cells that were infected with siNC. *P<0.05 vs. untreated cells or siNC group. (B) U87 cell proliferation is inhibited by siCOUP-TFII compared with siNC or the untreated group as demonstrated by cell counting, P<0.01 vs. siNC or the untreated group. COUP-TFII, chicken ovalbumin upstream promoter transcription factor II; MPC1, mitochondrial pyruvate carrier 1; NC, negative control; si, small-interfering.